From the North:  

Motorway A7, exit 22, Orange Sud. Take the Carpentras road. When arriving in Carpentras, take the Caromb road (D13). You will find the Domaine des Ecureuils on the left-hand side of the road.

   

From the South:

Motorway A7, exit Avignon Nord. Take the Carpentras road. When arriving in Carpentras, take the Orange road and then the Caromb road (D13). You will find the Domaine des Ecureuils on the left-hand side of the road. 

  

TGV from Brussels to Avignon, during the summer months, Thalys from Rotterdam and Amsterdam straight to Avignon.